Overview
Rheumatoid arthritis is an autoimmune disorder characterized by swollen and painful joints. It occurs when the immune system mistakenly attacks the tissue that lines the joints. Without treatment, it may eventually damage the entire joint. In addition to preventing to joint damage, prescription medicines, including nonsteroidal anti-inflammatory drugs and disease-modifying drugs, also help to alleviate pain and inflammation. Some natural remedies, including curcumin, may also help to reduce swelling and pain. Don't, however, use it in place of the drugs your doctor prescribes. Ask you doctor whether incorporating curcumin in your treatment plan will be beneficial for you.
Properties
Curcumin is a compound found in turmeric, a spice commonly used in cooking. It is also used as an alternative treatment for a variety of disorders, including osteoarthritis, menstrual pain and rheumatoid arthritis. Turmeric contains other biologically active compounds including volatile oils. However, the Mississippi Baptist Health Systems notes that curcumin is likely responsible for turmeric's anti-inflammatory effects, adding that it may even be as powerful as ibuprofen, a commonly taken over-the-counter pain reliever.
Administration
You can obtain curcumin by taking a turmeric supplement. Turmeric is often supplied as a powder, but you also take it in capsules or tablets. The University of Maryland Medical Center suggests taking 400 mg of a standardized extract of turmeric three times daily to help alleviate RA symptoms. Bear in mind that this is only a guideline. UMMC adds that some people combine turmeric with a plant-based enzyme known as bromelain. Talk to your pharmacist or doctor before taking turmeric to establish a suitable dose for you.
Effectiveness
An article published in a 2007 edition of "Advances and Experimental Medicine and Biology" noted that evidence suggests curcumin can prevent autoimmune diseases, including RA, by regulating the levels of certain inflammatory chemicals such as IL-1beta and IFN-gamma. The results of a study published in the November 2006 issue of "Arthritis and Rheumatism" showed that turmeric inhibits joint inflammation and joint destruction in a dose-dependent manner. However, the study was performed in an animal model of RA, not in people with this condition.
Safety Considerations
Turmeric is likely safe for most people, according to RxList.com. In addition, it listed on the U.S. Food and Drug Administration's "generally recognized as safe list." However, it may cause diarrhea and nausea. Mississippi Baptist Health Systems notes that taking turmeric for long periods may cause liver toxicity. Don't take turmeric if you have a liver problem or gallbladder disease. Avoid taking medicinal quantities of turmeric if you are pregnant or breast-feeding. It may interact with other medicines you may be taking, including anticoagulants.
source : livestrong.com
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